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Targeting the GLP-1 and GIP hormones, it is a weekly injection showing up to 20.9% average body weight reduction for participants in trials

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Proton pump inhibitors and H2 receptor antagonists, commonly used for gastroesophageal reflux disease and peptic ulcer disease, may affect vitamin B12 status through multiple mechanisms

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First, this analysis was based on aggregated arm-level data rather than individual participant data, which limited the ability to adjust for patient-level heterogeneity, including comorbidities and concomitant therapies